Silver Nanoparticles as a Novel Potential Preventive Agent against Bacterial Activity

Document Type : Original Article

Authors

1 Physics department, Faculty of Science, Zagazig University, Al-Sharqia, Egypt

2 Biophysics Branch-Department of Physics - faculty of science - Zagazig University

3 visual science Department, Research Institute of Ophthalmology, Giza, Egypt

4 Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, P.O.12622, Giza, Egypt

Abstract

Silver nanoparticles (AgNPs) have gained significant attention in diverse fields, including medicine, owing to their exceptional antibacterial, antiviral, and anti-inflammatory properties. Given the potential therapeutic uses of AgNPs, this study provides in depth analysis of the impact of silver nanoparticles on the tested Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Pseudomonas aeruginosa. The AgNPs were biologically synthesized by reducing silver nitrate with almond kernels water extract. Surface Plasmon Resonance (SPR) ~435 nm. XRD calculated particle sizes were 18.1 ± 3.5 nm while TEM sizes are 18.2 ± 4 nm for AgNPs.. silver nanoparticles (Ag NPs) exhibited a power full antimicrobial activity against the tested Gram-positive bacteria Staphylococcus aureus with inhibition zone rang (IZ=20.0 mm) and Gram-negative bacteria Pseudomonas aeruginosa (IZ= 23 mm). The obtained results indicate that the silver nanoparticles (Ag NPs) exhibited a powerful antimicrobial activity against the tested Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Pseudomonas aeruginosa which enable us to use this nanoparticle material in contact lenses preservation and packaging.

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