Synthesis and Characterization of Some 5-Bromouracil Metal ion Complexes

Yousuf, Marwa

doi:10.21608/bfszu.2024.236025.1322

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	Synthesis and Characterization of Some 5-Bromouracil Metal ion Complexes
Article 5, Volume 2024, Issue 2, July 2024, Page 40-53 PDF (1.8 MB)
Document Type: Original Article
DOI: 10.21608/bfszu.2024.236025.1322
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Author
Marwa Yousuf
Chemistry Department, Faculty of Science, Zagazig University
Abstract
A Five new complexes [Mg(BrU)2].8H2O (A), [Sr(BrU)2.(H2O) 2 ] (B), [Ca(BrU)2(H2O)2].H2O (C), [Pb(BrU)2] (D) and [Hg(BrU)2] (E) were prepared by the reaction of 5-bromoouracil ligand with MgCl2.6H2O, SrCl2.6H2O, CaCl2.2H2O, Pb(NO3)2 and HgCl2 salts, respectively. The metal complexes were characterized by conventional methods through their melting point, molar conductivity, elemental analysis, IR, UV- Vis., 1 H-NMR analyses. The obtained data indicated that the ligand undergoes keto ↔ enol tautomerism and behaves as mononegative bidentate donor and interacts with all metal ions . Thermal analysis indicate that the complexes degrade,more or less, through three main steps representing the dehdration of physically absorbed and coordinated water molecules then the decomposition of the unhydrous species leading to metal oxides as final products. Some of the prepared complexes were tested against gram positive and gram negative bacteria and fungii which showed effective activity. Keywords: 5-Bromoouracil–M2+ Complexes, IR, Thermal Analyses, 1H NMR, antimicrobial and antifungal activities.
Keywords
5-Bromoouracil–M2+ Complexes; IR; Thermal Analyses; 1H NMR; antimicrobial and antifungal activities
Main Subjects
Basic and applied research of Chemistry,


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